吉西他滨是一种 DNA合成 抑制剂，抑制 BxPC-3，Mia Paca-2，PANC-1，PL-45 和 AsPC-1细胞生长的 IC50分别为 37.6, 42.9, 92.7, 89.3 and 131.4 nM，是一种用于治疗多种癌症的化疗药物。这些癌症包括乳腺癌、卵巢癌、非小细胞肺癌、胰腺癌和膀胱癌。它是通过缓慢静脉注射给药的。
4-Amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one hydrochloride
((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl benzoate
((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate
((2R,3R)-3-(Benzoyloxy)-4,4-difluoro-5-oxotetrahydrofuran-2-yl)methyl benzoate
Ethyl 2-bromo-2,2-difluoroacetate
Methyl 2-bromo-2,2-difluoroacetate
tert-Butyldimethylsilyl trifluoromethanesulfonate
(R)-Ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-difluoro-3-hydroxypropanoate
(S)-2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde
4-(Bis(trimethylsilyl)amino)pyrimidin-2(1H)-one
