Deubiquitinating enzymes (DUBs), also known as deubiquitinating peptidases, deubiquitinating isopeptidases, deubiquitinases, ubiquitin proteases, ubiquitin hydrolases, ubiquitin isopeptidases, are a large group of proteases that cleave ubiquitin from proteins and other molecules. Ubiquitin is attached to proteins in order to regulate the degradation of proteins via the proteasome and lysosome; coordinate the cellular localisation of proteins; activate and inactivate proteins; and modulate protein-protein interactions.[3][4][5] DUBs can reverse these effects by cleaving the peptide or isopeptide bond between ubiquitin and its substrate protein. In humans there are nearly 100 DUB genes, which can be classified into two main classes: cysteine proteases and metalloproteases. The cysteine proteases comprise ubiquitin-specific proteases (USPs), ubiquitin C-terminal hydrolases (UCHs), Machado-Josephin domain proteases (MJDs) and ovarian tumour proteases (OTU). The metalloprotease group contains only the Jab1/Mov34/Mpr1 Pad1 N-terminal+ (MPN+) (JAMM) domain proteases.

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882257-11-6

BD398781882257-11-698+%

¥390.001mg常备现货

1572414-83-5

BD3056291572414-83-598+%

¥390.001mg常备现货

1431280-51-1

BD2973881431280-51-198+%

¥1275.001mg常备现货

1247819-59-5

BD2545081247819-59-598+%

¥400.005mg常备现货

668467-91-2

BD630813668467-91-298+%

¥475.005mg常备现货

63388-44-3

BD33486963388-44-398+%

¥746.001mg常备现货

1009817-63-3

BD3046911009817-63-398+%

¥370.005mg常备现货

2645-32-1

BD2895802645-32-198+%

¥400.005mg常备现货

157654-67-6

BD764552157654-67-698+%

¥425.005mg常备现货

924296-17-3

BD631018924296-17-398+%

¥1085.001mg

1426944-49-1

BD6302661426944-49-198+%

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1247825-37-1

BD6300531247825-37-198+%

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30675-13-9

BD9237530675-13-995+%

¥273.001mg

924296-19-5

BD631020924296-19-598+%

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924296-18-4

BD631019924296-18-498+%

¥1371.001mg

1381291-36-6

BD6302041381291-36-698+%

¥1166.001mg

856243-80-6

BD408267856243-80-698+%

¥292.001mg

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