波普瑞韦是一种口服有效的选择性的 HCV NS3 protease 抑制剂,酶实验中Ki 为 14 nM,在含细胞体系的复制实验中,EC90 为 350 nM,是一种蛋白酶抑制剂,用于治疗丙型肝炎病毒(HCV)基因型1引起的肝炎。它与丙型肝炎病毒非结构蛋白3活性位点结合。

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